Fem-Dophilus® contains two patented and clinically documented probiotic strains, Lactobacillus rhamnosus, GR-1® and Lactobacil/us reuteri, RC-14®. In randomized clinical trials, 75% of women in the GR-1®/RC-14®probiotic group experienced significant improvement in vaginal flora composition, while only 34% of women in the placebo (non-probiotic) group experienced similar improvement.