Our central nervous system, (CNS), is a complex matrix of neurons, neurochemicals and hormones. There are two kinds of neurotransmitters (NT) – inhibitory and excitatory. Excitatory neurotransmitters are what stimulate the brain. Those that calm the brain and help create balance are called inhibitory. Inhibitory neurotransmitters work synergistically to counter balance the excitatory neurotransmitters. These inhibitory NTs balance mood and are easily depleted when the excitatory neurotransmitters are overactive. Calming Cream™ is designed to naturally increase the levels of the calming reducing neurotransmitters in the brain such as dopamine, serotonin and GABA.